Wenjing Sun

Dr. Wenjing Sun's photo

Wenjing Sun

Assistant Professor, Department of Neuroscience

Wenjing.Sun@osumc.edu

(614) 293-2672

696 Biomedical Research Tower
460 W. 12th Avenue
Columbus, OH 43210

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Areas of Expertise

  • Molecular and Cellular Neuroscience
  • Systems Neuroscience
  • Neurotrauma, Neurological Disorders, and Gene/Clinical Therapies
  • Developmental Neuroscience and Genetics

Education

  • PhD: Purdue University
  • Postdoctoral Training: Harvard University, University Clinic Bonn (Germany)

Current Research Description

Myelination is essential for rapid transmission of electrical impulses along axons and also plays a pivotal role in maintaining precise spatiotemporal activity patterns within neural networks. Emerging evidence demonstrates that neuronal activity positively regulates myelin formation. However, the underlying cellular and molecular mechanisms of neuronal activity-dependent myelination have not yet been fully elucidated. In turn, there is currently no effective therapeutic intervention to promote remyelination after trauma or disease. Our lab aims to identify molecular mediators that regulate myelin development and repair, and to decipher cellular and molecular mechanisms underlying this multi-step process. In order to do so, we employ a multidisciplinary approach that combines genetics, experimental models of CNS trauma and demyelination, tract tracing, in vivo and ex vivo electrophysiology, optogenetics, calcium imaging, glutamate uncaging and behavioral tests.

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