John Sheridan
Professor, Division of Biosciences
Institute for Behavioral Medicine Research
460 Medical Center Drive
Columbus, OH 43210
Areas of Expertise
- Stress and Neuroimmunology
- Molecular and Cellular Neuroscience
- Behavioral Neuroscience
Education
- Postdoctoral Training: Rutgers University
Current Research Description
My current research focus has been on studying how psychosocial stressors are perceived by the brain and subsequently affect gene expression in the immune, behavioral, and pain responses. Using a model of social defeat, in which aggressive interactions occur among stable cohorts of mice resulting is cutaneous wounding, we have shown that repeated defeat results in enhanced inflammatory responses, the development of anxiety-like behavior and increased pain sensitivity. Recent studies are directed at identifying potential epigenetic mechanisms that modulate inflammatory responses.