Bin Gu

Dr.  Bin Gu's photo

Bin Gu

Assistant Professor, Department of Neuroscience

Bin.Gu@osumc.edu

(614) 685-0586

612 Biomedical Research Tower
460 W. 12th Avenue
Columbus, OH 43210

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Areas of Expertise

  • Epilepsy and sudden unexpected death in epilepsy (SUDEP)
  • In vivo electrophysiology
  • Genetic and molecular Neuroscience
  • Molecular and Cellular Neuroscience
  • Developmental Neuroscience and Genetics
  • Neurotrauma, Neurological Disorders, and Gene/Clinical Therapies

Education

  • PhD: Duke University
  • Postdoctoral training: The University of North Carolina, Chapel Hill

Current Research Description

Epilepsies are a highly heritable yet clinically heterogeneous group of neurological disorders. Seizures are commonly drug-resistant, comorbid with autistic and psychiatric conditions and increase the risk of death, also known as SUDEP (Sudden Unexpected Death in Epilepsy). SUDEP is the leading cause of death in epileptic individuals and second only to stroke in the number of life years lost. My overarching goal is to understand the genetic and pathophysiologic basis of epilepsy, SUDEP, and related neurological disorders. This information will allow me to further explore molecular control of brain synchronization, identify biomarkers, and finally develop therapeutics for epilepsy and SUDEP. My lab tackles these challenges using combination of interdisciplinary approaches including systems genetics (e.g. Collaborative Cross mice), molecular biology, pharmacology, electrophysiology, optogenetics, and behavioral assays.

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